Diagnostic Performance of the "Lab-Score" in Predicting Severe and Invasive Bacterial Infections in Well-Appearing Young Febrile Infants.
- Bressan, Silvia
- Gomez, B
- Mintegi, S
- DA DALT, Liviana
- Blazquez, D
- Olaciregui, I
- de la Torre, M
- Palacios, M
- Berlese, P
- Ruano, A.
DOIAbstract
BACKGROUND AND OBJECTIVES: The "Lab-score" combining C-reactive protein, procalcitonin and urine dipstick results has recently been derived and validated as an accurate tool for predicting severe bacterial infections (SBI) in children with fever without source (FWS). We aimed to assess the "Lab-score" usefulness in predicting SBI, and especially invasive bacterial infections (IBI) in well-appearing infants <3 months with FWS. METHODS: A multicenter retrospective study was carried in 7 pediatric emergency departments in Spain and Italy. An SBI was defined as isolation of a bacterial pathogen from urine, blood, cerebrospinal fluid, or stools; an IBI as isolation of a bacterial pathogen from blood or cerebrospinal fluid. The diagnostic charact...
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